Family · Pharmaceutical analytical standards
Abiraterone
An inhibitor of the CYP17 enzyme, blocking androgen production even outside the testes. Designed in the United Kingdom at the Institute of Cancer Research, it was approved in 2011 for advanced prostate cancer. This family brings together the active ingredient, metabolites, labelled standards, nitrosamines and other impurities.
Did you know?The idea came from the antifungal ketoconazole, which blocked the same enzyme: in the 1995 scientific paper the new molecule appeared simply as 'compound 3'.
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