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Services

Our services.

Synthesis on request and research and development services for drug discovery, diagnostics and research.

01

Custom synthesis

Impurities and metabolites not available on the market, and isolation of single enantiomers. A structure, a CAS number or a literature reference is all it takes.

Request a synthesis
  • Process and degradation impurities
  • N-nitroso compounds and NDSRIs specific to the API
  • Metabolites and labelled standards
  • Isolation and purification of single enantiomers
  • Full CoA with IR, MS, 1H and 13C-NMR and HPLC (ESI-MS and MALDI-TOF for peptides)
  • From milligrams to grams, with repeat orders

02

Custom monoclonal antibodies

Rabbit recombinant monoclonal antibodies developed to order for research, diagnostics and early therapeutic discovery, also against difficult targets such as small molecules. Every project starts from the target and the intended use: you receive a feasibility assessment, the proposed strategy and a quote by phase.

Request this service
  • Immunogen preparation, including hapten synthesis
  • Selection of the best clones directly from single plasma cells
  • High affinity and consistent lots thanks to recombinant production
  • Quote by phase, with a part linked to agreed results

03

Antibody services

For existing antibodies, including your own: conjugation, recombinant production in quantity and engineering to improve performance in your assay.

Request this service
  • Antibody conjugation
  • Recombinant production, also at scale
  • Antibody engineering
  • Technical support in choosing the format

04

Kinase inhibitor profiling

The potency of your compounds measured on a broad panel of human kinases, with the dissociation constant (Kd) rather than percent inhibition only. Full, focused or custom panels, with results in 7 working days (14 for complex projects).

Request this service
  • Full panel of over 230 human kinases
  • Focused panels: mini panel, tyrosine kinases, CDK, CK1
  • Custom selection of kinases
  • Quantitative results (Kd) from the start of the project

05

Carbonic anhydrase inhibitor profiling

Selectivity of your inhibitors on all 11 enzymatically active human carbonic anhydrase isoforms, with quantitative dissociation constants (Kd).

Request this service
  • All 11 active human isoforms in one panel
  • Quantitative Kd, comparable across isoforms
  • Full panel or custom selection
  • Results in 7 working days

06

High-throughput screening and custom assays

High-throughput screening (HTS) campaigns based on the profiling assays, or an assay developed to order for your target. You can choose from the available compound libraries or use your own; results are quantitative from the start.

Request this service
  • Libraries to find new scaffolds: about 10,000 and 120,000 compounds
  • Focused libraries: kinase inhibitors and approved drugs
  • Screening of your own library
  • Custom assay ready in about three months
  • Milestone and risk-sharing agreements

Request

Request a research and development service.

Choose the service and fill in the fields: we reply with feasibility, lead time and a quote. Custom synthesis has its own form.

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Name, CAS or code, with quantities. We reply with a single quote for every line, including items not in the catalogue.

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