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Family · Pharmaceutical analytical standards

Agomelatine

An antidepressant with an original mechanism: it activates the melatonin receptors MT1 and MT2 and blocks the serotonin 5-HT2C receptors, indirectly increasing noradrenaline and dopamine in the frontal cortex. Approved in the European Union in 2009 for major depression. This family brings together the active ingredient, labelled standards, nitrosamines and other impurities.

Did you know?It is a copy of melatonin, the sleep hormone, in which the indole ring is replaced by a naphthalene. Development for the United States market, by contrast, was stopped in 2011.

AgomelatineGo to the active ingredient →
AgomelatineActive ingredientAgomelatineCat. No. P-A055-001CAS 138112-76-2
Agomelatine-d6Isotopically labelledAgomelatine-d6Cat. No. P-A055-002CAS 1079389-42-6

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