Family · Pharmaceutical analytical standards

Alanosine

A natural antibiotic that mimics an amino acid, described in 1966 as an antiviral and antitumour agent: it blocks purine synthesis by inhibiting the enzyme adenylosuccinate synthetase. It has been studied as an anticancer drug, especially against tumours lacking the enzyme MTAP. This family brings together other impurities.

Did you know?The bacterium that makes it, Streptomyces alanosinicus, was isolated from a soil sample in Brazil and is named after alanosine itself; it also makes a second antibiotic, spicamycin.