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Family · Pharmaceutical analytical standards

Aliskiren

The first drug in the class of direct renin inhibitors, which block the enzyme that starts the hormonal cascade through which the kidney regulates blood pressure. Designed with the help of crystallography and molecular modelling, it was approved in 2007 in the US and Europe for hypertension. This family brings together the active ingredient and other impurities.

Did you know?Its target had been known for over a century: in the late 19th century Robert Tigerstedt and Per Bergman saw that kidney extracts injected into rabbits raised blood pressure, and named the active substance renin.

Aliskiren HemifumarateGo to the active ingredient →

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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.