Family · Pharmaceutical analytical standards
Alvespimycin
A semi-synthetic derivative of geldanamycin, an antibiotic produced by the bacterium Streptomyces hygroscopicus; it inhibits the protein Hsp90 and was studied in the 2000s against solid tumours and leukaemias, without reaching approval. This family brings together the active ingredient.
Did you know?Hsp90 is a heat shock protein that acts as a chaperone, helping other proteins to fold: blocking it makes many proteins that tumour cells depend on break down.
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