Family · Pharmaceutical analytical standards
Aminoglutethimide
A glutethimide derivative introduced in 1960 as an anticonvulsant and withdrawn in 1966; from 1969 it was repurposed for Cushing's syndrome and breast cancer, because it blocks the production of steroid hormones. This family brings together the active ingredient.
Did you know?It was the first aromatase inhibitor to be discovered and used clinically: its effect on the adrenal glands came to light by chance in 1963, in a young girl taking it for epilepsy.
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