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Family · Pharmaceutical analytical standards

Amphotericin B

A polyene antifungal that binds to ergosterol in fungal membranes and opens pores in them: isolated in 1955 and in medical use since 1958, it remains a mainstay for the most serious fungal infections. This family brings together the active ingredient, pharmacopoeial impurities, labelled standards and other impurities.

Did you know?It is made by a bacterium, Streptomyces nodosus, found in a soil sample collected along the Orinoco River in Venezuela. The name recalls its amphoteric nature: it can behave as both an acid and a base.

Amphotericin BGo to the active ingredient →

EDQM standards 3

The official European Pharmacopoeia standards for this family.

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