Family · Pharmaceutical analytical standards
Anagliptin
A DPP-4 inhibitor (gliptin) for type 2 diabetes, approved in Japan in 2012: it helps control blood glucose by prolonging the action of incretins, the gut hormones released after meals. This family brings together the active ingredient, labelled standards, nitrosamines and other impurities.
Did you know?Its crystal structure bound to the DPP-4 enzyme shows that it does not mimic the enzyme's natural substrates: it attaches only through non-covalent interactions, for instance between its cyano group and a serine in the active site.
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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
