Family · Pharmaceutical analytical standards

Atomoxetine

A selective noradrenaline reuptake inhibitor, approved in the United States in 2002 as the first non-stimulant medicine for attention deficit hyperactivity disorder (ADHD). This family brings together the active ingredient, pharmacopoeial impurities, metabolites, labelled standards, nitrosamines and other impurities.

Did you know?It was originally called tomoxetine: the FDA asked for a new name because it looked too much like tamoxifen, an anticancer drug, with a risk of mix-ups at the pharmacy.

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Active ingredientAtomoxetine HydrochlorideCat. No. P-A209-001CAS 82248-59-7

Pharmacopoeial impurityAtomoxetine EP Impurity B HydrochlorideCat. No. P-A209-002CAS 82857-39-4

Pharmacopoeial impurityAtomoxetine EP Impurity DCat. No. P-A209-003CAS 1643684-02-9

Pharmacopoeial impurityAtomoxetine EP Impurity A HydrochlorideCat. No. P-A209-005CAS 873310-33-9

Pharmacopoeial impurityAtomoxetine EP Impurity BCat. No. P-A209-006CAS 105314-53-2

Pharmacopoeial impurityAtomoxetine EP Impurity C HydrochlorideCat. No. P-A209-007CAS 1643684-06-3

Pharmacopoeial impurityAtomoxetine EP Impurity D HydrochlorideCat. No. P-A209-008CAS 1643684-05-2

Pharmacopoeial impurityAtomoxetine EP Impurity ECat. No. P-A209-009CAS 17199-29-0

Pharmacopoeial impurityAtomoxetine EP Impurity F HClCat. No. P-A209-010

Pharmacopoeial impurityAtomoxetine EP Impurity F Oxalate SaltCat. No. P-A209-011

Pharmacopoeial impurityAtomoxetine EP Impurity GCat. No. P-A209-012CAS 1010818-93-5

Pharmacopoeial impurityAtomoxetine EP Impurity G DiHCl (Mixture of Diastereomers)Cat. No. P-A209-013

Pharmacopoeial impurityAtomoxetine EP Impurity H (S-Isomer)Cat. No. P-A209-014CAS 114133-37-8

Pharmacopoeial impurityAtomoxetine EP Impurity H (R-Isomer)Cat. No. P-A209-015CAS 115290-81-8

Pharmacopoeial impurityrac-Atomoxetine EP Impurity C HClCat. No. P-A209-016CAS 873310-31-7

Pharmacopoeial impurityrac-Atomoxetine EP Impurity D HydrochlorideCat. No. P-A209-017CAS 873310-28-2

Metabolite4'-Hydroxy Atomoxetine GlucuronideCat. No. P-A209-018CAS 540729-08-6

Isotopically labelled4'-Hydroxy Atomoxetine-d3 HemioxalateCat. No. P-A209-019

Isotopically labelled4'-Hydroxy Atomoxetine beta-D-Glucuronide-d3Cat. No. P-A209-021

Isotopically labelledAtomoxetine EP Impurity B-d3 HClCat. No. P-A209-022CAS 1217703-95-1

Isotopically labelledAtomoxetine-d3 HClCat. No. P-A209-023CAS 1217776-38-9

Isotopically labelledN-Nitroso Atomoxetine EP Impurity B-d3Cat. No. P-A209-024

Isotopically labelledN-Nitroso Atomoxetine-d3Cat. No. P-A209-025

Isotopically labelledrac-Atomoxetine-d5 HydrochlorideCat. No. P-A209-026CAS 1398065-95-6

Isotopically labelledrac-N-Nitroso-Atomoxetine d3Cat. No. P-A209-027

NitrosamineN,N-Dinitroso Atomoxetine EP Impurity GCat. No. P-A209-028

NitrosamineN-Nitroso AtomoxetineCat. No. P-A209-029CAS 3028194-77-3

NitrosamineN-Nitroso Atomoxetine EP Impurity ACat. No. P-A209-030

NitrosamineN-Nitroso Atomoxetine EP Impurity BCat. No. P-A209-031

NitrosamineN-Nitroso Atomoxetine EP Impurity CCat. No. P-A209-032

NitrosamineN-Nitroso Atomoxetine EP Impurity DCat. No. P-A209-033

NitrosamineN-Nitroso Atomoxetine EP Impurity FCat. No. P-A209-034

NitrosamineN-Nitroso Atomoxetine EP Impurity GCat. No. P-A209-035

NitrosamineN-Nitroso Atomoxetine EP Impurity H (R-Isomer)Cat. No. P-A209-036

ImpurityAtomoxetine Impurity 1Cat. No. P-A209-038CAS 114446-47-8

Impurity3-Chloro-1-phenylpropanolCat. No. P-A209-039CAS 18776-12-0

ImpurityAtomoxetine Impurity 2 HydrochlorideCat. No. P-A209-040CAS 1011-59-2

Impurity4-Hydroxy Atomoxetine (S-Isomer) OxalateCat. No. P-A209-041

Impurity4-Hydroxy Atomoxetine OxalateCat. No. P-A209-042CAS 457634-21-8

ImpurityAtomoxetine 4-Hydroxy HCl SaltCat. No. P-A209-043CAS 457634-24-1

ImpurityAtomoxetine 4-Hydroxy ImpurityCat. No. P-A209-044CAS 435293-66-6

ImpurityAtomoxetine Impurity 3Cat. No. P-A209-045

ImpurityAtomoxetine Impurity 4 OxalateCat. No. P-A209-046

ImpurityAtomoxetine Impurity 5 HydrochlorideCat. No. P-A209-047

ImpurityAtomoxetine Impurity 6Cat. No. P-A209-048

ImpurityAtomoxetine Impurity 7 (R-Isomer)Cat. No. P-A209-049CAS 100306-33-0

ImpurityAtomoxetine Impurity 8 HydrochlorideCat. No. P-A209-050

ImpurityAtomoxetine Impurity 9 (Mixture of Diastereomers)Cat. No. P-A209-051

ImpurityAtomoxetine Impurity 10 HydrochlorideCat. No. P-A209-052

ImpurityAtomoxetine Impurity 11 HydrochlorideCat. No. P-A209-053

ImpurityAtomoxetine N-Desmethyl (S Isomer) HCl SaltCat. No. P-A209-054

ImpurityAtomoxetine N-hydroxyamine ImpurityCat. No. P-A209-055

ImpurityAtomoxetine PD3 ImpurityCat. No. P-A209-056

ImpurityAtomoxetine PD5 Impurity (meta-hydroxy)Cat. No. P-A209-057

ImpurityAtomoxetine PD6 ImpurityCat. No. P-A209-058

ImpurityAtomoxetine Urea ImpurityCat. No. P-A209-060

ImpurityAtomoxetine Impurity 12 HydrochlorideCat. No. P-A209-061CAS 42064-62-0

ImpurityN-Formyl AtomoxetineCat. No. P-A209-062CAS 2376668-89-0

ImpurityN-methyl-3-chloro-3-phenylpropylamine HydrochlorideCat. No. P-A209-063CAS 128036-32-8

ImpurityN-Methyl-3-phenylprop-2-en-1-amine hydrochlorideCat. No. P-A209-064CAS 116939-14-1

Impurityrac-Atomoxetine Impurity 13Cat. No. P-A209-065CAS 881995-45-5

Impurityo-CresolCat. No. P-A209-066CAS 95-48-7

Impurity3-[Benzyl(methyl)amino]propiophenone HydrochlorideCat. No. P-A209-067CAS 5409-62-1

Impurityrac-Atomoxetine HClCat. No. P-A209-068CAS 82857-40-7

Impurityrac-N-Desmethyl Atomoxetine HClCat. No. P-A209-069CAS 881995-46-6

EDQM standards 4

The official European Pharmacopoeia standards for this family.

ImpurityAtomoxetine for impurity A identification CRSEDQM code Y0001587Family Atomoxetine

Reference substanceAtomoxetine hydrochloride CRSEDQM code Y0001586Family Atomoxetine

ImpurityAtomoxetine impurity B CRSEDQM code Y0001588Family Atomoxetine

ImpurityAtomoxetine impurity D CRSEDQM code Y0001589Family Atomoxetine

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