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Family · Pharmaceutical analytical standards

Auristatin F

A synthetic peptide of the auristatin family, an extremely potent tubulin inhibitor that blocks cell division: too toxic on its own, in its monomethyl form (MMAF) it is attached to monoclonal antibodies that carry it to tumour cells, as in belantamab mafodotin for multiple myeloma. This family brings together the active ingredient, labelled standards and other impurities.

Did you know?It descends from the dolastatins, peptides discovered in a large marine mollusc with no external shell, the wedge sea hare (Dolabella auricularia).

Auristatin FGo to the active ingredient →
Auristatin FActive ingredientAuristatin FCat. No. P-A216-001CAS 163768-50-1

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