Family · Pharmaceutical analytical standards
Avapritinib
A KIT and PDGFRA kinase inhibitor, approved in the United States in January 2020 and in Europe the same year for gastrointestinal stromal tumours (GIST) with PDGFRA exon 18 mutations, and later also for systemic mastocytosis. This family brings together the active ingredient, labelled standards and other impurities.
Did you know?It was the first targeted therapy approved by the FDA for the rare PDGFRA D842V mutation, a genetic defect that makes these tumours unresponsive to the drugs used before.
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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
