Family · Pharmaceutical analytical standards
Azamulin
A semi-synthetic derivative of pleuromutilin, an antibiotic produced by the fungus Pleurotus mutilus, carrying an added triazole group; today it is known mainly in the laboratory as a selective, irreversible inhibitor of the liver's CYP3A enzymes. This family brings together the active ingredient.
Did you know?Its selectivity for CYP3A enzymes comes from the pleuromutilin part of the molecule, not from the triazole: it is about 100 times less active on most other P450 enzymes, and it became a tool for studying drug metabolism.
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