Family · Pharmaceutical analytical standards
Belzutifan
An oral inhibitor of HIF-2 alpha, a protein that drives the growth of some tumours when oxygen is lacking or when the VHL gene does not work. Approved in the United States in 2021, it was the first medicine for tumours associated with von Hippel-Lindau disease. This family brings together the active ingredient, metabolites, labelled standards and other impurities.
Did you know?It grew out of Nobel-winning science: William Kaelin and Peter Ratcliffe showed that the VHL protein controls HIF levels, work on how cells sense oxygen that earned the 2019 Nobel Prize in Medicine, shared with Gregg Semenza.
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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
