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Family · Pharmaceutical analytical standards

Bosutinib

A BCR-ABL and Src tyrosine kinase inhibitor, approved in the United States in 2012 for Philadelphia chromosome-positive chronic myeloid leukaemia, initially in patients resistant or intolerant to previous therapies. This family brings together the active ingredient, labelled standards, nitrosamines and other impurities.

Did you know?It came from a series of molecules designed to block the Src kinase (its development code was SKI-606) and turned out to be a potent inhibitor of BCR-ABL too, the protein that drives chronic myeloid leukaemia.

BosutinibGo to the active ingredient →
BosutinibActive ingredientBosutinibCat. No. P-B101-001CAS 380843-75-4
Bosutinib-d8Isotopically labelledBosutinib-d8Cat. No. P-B101-002CAS 2733145-45-2

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