Family · Pharmaceutical analytical standards
Bosutinib
A BCR-ABL and Src tyrosine kinase inhibitor, approved in the United States in 2012 for Philadelphia chromosome-positive chronic myeloid leukaemia, initially in patients resistant or intolerant to previous therapies. This family brings together the active ingredient, labelled standards, nitrosamines and other impurities.
Did you know?It came from a series of molecules designed to block the Src kinase (its development code was SKI-606) and turned out to be a potent inhibitor of BCR-ABL too, the protein that drives chronic myeloid leukaemia.
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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
