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Family · Pharmaceutical analytical standards

Bretylium

A class III antiarrhythmic, a quaternary ammonium salt that accumulates in sympathetic nerve endings and blocks their release of noradrenaline; in the 1980s and 1990s it was used in emergencies against resistant ventricular fibrillation and tachycardia. This family brings together other impurities.

Did you know?It was born in 1959 as an antihypertensive; its second life as an antiarrhythmic is owed to Marvin Bacaner of the University of Minnesota, who patented this use in 1969.

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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.