Family · Pharmaceutical analytical standards
Cilastatin
An inhibitor of dehydropeptidase I, a kidney enzyme that breaks down the antibiotic imipenem: since 1985 it has been given together with imipenem to prevent its breakdown and keep it active. This family brings together the active ingredient, pharmacopoeial impurities, labelled standards and other impurities.
Did you know?On its own it has no antibacterial activity. The antibiotic it protects, imipenem, derives from thienamycin, produced by the bacterium Streptomyces cattleya and described in 1976.
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EDQM standards 3
The official European Pharmacopoeia standards for this family.
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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
