Family · Pharmaceutical analytical standards
Cilostazol
A phosphodiesterase 3 (PDE3) inhibitor with antiplatelet and vasodilating effects, approved in Japan in 1988 for symptoms of peripheral arterial disease, then in the United States in 1999 and in the UK in 2001 for intermittent claudication, leg pain when walking. This family brings together the active ingredient, pharmacopoeial impurities, metabolites, labelled standards, nitrosamines and other impurities.
Did you know?Besides inhibiting PDE3 it also blocks the uptake of adenosine by cells, a dual action that sets it apart from other PDE3 inhibitors such as milrinone.
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