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Cinacalcet

A calcimimetic that makes the calcium-sensing receptor of the parathyroid glands more responsive, so the glands release less parathyroid hormone. Approved in 2004, it is used for secondary hyperparathyroidism in dialysis patients and for high calcium caused by parathyroid carcinoma. This family brings together the active ingredient, pharmacopoeial impurities, metabolites, labelled standards, nitrosamines and other impurities.

Did you know?It was the first allosteric modulator of a G protein-coupled receptor (GPCR) to reach the market: it does not occupy the calcium site but binds elsewhere and amplifies calcium's effect.

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Active ingredientCinacalcet HydrochlorideCat. No. P-C166-001CAS 364782-34-3

Impurity(R)-1-(1-Naphthyl)ethylamine HydrochlorideCat. No. P-C166-002CAS 82572-04-1

ImpurityBenzyl[(R)-1-(1-naphthyl)ethyl]amine HydrochlorideCat. No. P-C166-003CAS 163831-65-0

Pharmacopoeial impurityCinacalcet USP Related Compound D HydrochlorideCat. No. P-C166-004CAS 1217809-88-5

Pharmacopoeial impurityCinacalcet USP RC ECat. No. P-C166-005CAS 78573-45-2

Metaboliterac-Cinacalcet Metabolite 1 (Mixture of Diastereomers)Cat. No. P-C166-006

Isotopically labelledCinacalcet-d3 HClCat. No. P-C166-007CAS 2749807-20-1

Isotopically labelledCinacalcet-d4 HydrochlorideCat. No. P-C166-008CAS 2514927-75-2

Isotopically labelledN-Nitroso Cinacalcet-d3Cat. No. P-C166-009

Isotopically labelledrac-Cinacalcet-d3 HClCat. No. P-C166-010CAS 1185097-33-9

NitrosamineN-Nitroso CinacalcetCat. No. P-C166-011CAS 3036581-83-3

ImpurityCinacalcet Impurity 1Cat. No. P-C166-012CAS 82258-76-2

Impurity1-(Naphthalen-1-yl)ethanone oximeCat. No. P-C166-013CAS 1956-40-7

Impurity1-(Naphthalen-2-yl)ethan-1-amineCat. No. P-C166-014CAS 1201-74-7

Impurity1-(Tosyloxy)-3-(trifluoromethyl)benzeneCat. No. P-C166-015CAS 131086-40-3

ImpurityCinacalcet Impurity 2Cat. No. P-C166-016CAS 136908-26-4

Impurity2-[3-(Trifluoromethyl)phenyl]propanalCat. No. P-C166-017CAS 1034094-54-6

Impurity3-(2-(Trifluoromethyl)phenyl)propan-1-olCat. No. P-C166-018CAS 191155-81-4

ImpurityCinacalcet Related Compound JCat. No. P-C166-019CAS 585-50-2

Impurity3-(3-Methylphenyl)propan-1-olCat. No. P-C166-020CAS 111171-94-9

ImpurityCinacalcet Impurity 3Cat. No. P-C166-021CAS 217483-10-8

Impurity3-(Trifluoromethyl)benzenepropanalCat. No. P-C166-022CAS 21172-41-8

ImpurityCinacalcet Impurity 4Cat. No. P-C166-023CAS 29690-38-8

Impurity3-(Trifluoromethyl)cinnamic AcidCat. No. P-C166-024CAS 779-89-5

Impurity3-[2-(trifluoromethyl)phenyl]propanalCat. No. P-C166-025CAS 376641-58-6

ImpurityCinacalcet Impurity 5Cat. No. P-C166-026CAS 329-02-2

ImpurityCinacalcet Impurity 6Cat. No. P-C166-027CAS 113048-69-4

Pharmacopoeial impurityCinacalcet USP Related Compound ACat. No. P-C166-028CAS 21172-43-0

Impurity3-[4-(trifluoromethyl)phenyl]propan-1-olCat. No. P-C166-029CAS 180635-74-9

Impurity3-[4-(trifluoromethyl)phenyl]propanalCat. No. P-C166-030CAS 166947-09-7

Impurity3-Phenylpropyl 4-methylbenzenesulfonateCat. No. P-C166-031CAS 3742-75-4

Impurity4-(Trifluoromethyl)benzaldehydeCat. No. P-C166-032CAS 455-19-6

ImpurityCinacalcet Impurity 8Cat. No. P-C166-033CAS 29417-96-7

ImpurityBenzyl[(R)-1-(1-naphthyl)ethyl]amineCat. No. P-C166-034CAS 66469-40-7

ImpurityCinacalcet 5,6-Dihydro Racemate BaseCat. No. P-C166-035CAS 802918-47-4

ImpurityCinacalcet Impurity 9 HydrochlorideCat. No. P-C166-036CAS 1020414-33-8

ImpurityCinacalcet Impurity 10 HydrochlorideCat. No. P-C166-037

Pharmacopoeial impurityCinacalcet USP Related Compound B HydrochlorideCat. No. P-C166-038

ImpurityCinacalcet Impurity 12Cat. No. P-C166-039

ImpurityCinacalcet Impurity 13Cat. No. P-C166-040

ImpurityCinacalcet Impurity 13 HydrochlorideCat. No. P-C166-041

ImpurityCinacalcet Impurity 14 HydrochlorideCat. No. P-C166-042

ImpurityCinacalcet Impurity 15 HydrochlorideCat. No. P-C166-043

Impurityrac-Cinacalcet Impurity 16 HydrochlorideCat. No. P-C166-044CAS 2514708-62-2

ImpurityCinacalcet Impurity 17Cat. No. P-C166-045

ImpurityCinacalcet Impurity 18 HydrochlorideCat. No. P-C166-046

ImpurityCinacalcet Impurity 19 Fumarate (Mixture of Diastereomers)Cat. No. P-C166-047

ImpurityCinacalcet Impurity 20Cat. No. P-C166-048

ImpurityCinacalcet Impurity 21Cat. No. P-C166-049

ImpurityCinacalcet Impurity 22 HydrochlorideCat. No. P-C166-050

ImpurityCinacalcet Impurity 23Cat. No. P-C166-051

ImpurityCinacalcet Impurity 24Cat. No. P-C166-052

Pharmacopoeial impurityCinacalcet USP Related Compound CCat. No. P-C166-053CAS 1428118-39-1

ImpurityCinacalcet Impurity 25Cat. No. P-C166-054

ImpurityCinacalcet Impurity 26 HydrochlorideCat. No. P-C166-055CAS 2726596-64-9

ImpurityCinacalcet Impurity 27Cat. No. P-C166-056CAS 22038-83-1

ImpurityCinacalcet Impurity 28Cat. No. P-C166-057

ImpurityCinacalcet Impurity 29Cat. No. P-C166-058

ImpurityCinacalcet Impurity 30Cat. No. P-C166-059

ImpurityCinacalcet Impurity 31Cat. No. P-C166-060

ImpurityCinacalcet Impurity 31 HydrochlorideCat. No. P-C166-061CAS 938177-81-2

ImpurityCinacalcet Impurity 32 (Mixture of Diastereomers)Cat. No. P-C166-062

ImpurityCinacalcet Impurity 33Cat. No. P-C166-063CAS 1344557-18-1

ImpurityCinacalcet Impurity 34Cat. No. P-C166-064

ImpurityCinacalcet Impurity 35Cat. No. P-C166-065

ImpurityCinacalcet Impurity 36Cat. No. P-C166-066

ImpurityCinacalcet Impurity 37Cat. No. P-C166-067CAS 1622173-75-4

ImpurityCinacalcet Impurity 38Cat. No. P-C166-068

Impurityrac-Cinacalcet Impurity 39 HydrochlorideCat. No. P-C166-069CAS 1622173-72-1

ImpurityCinacalcet Impurity 40Cat. No. P-C166-070

ImpurityCinacalcet Impurity 41Cat. No. P-C166-071CAS 2055116-43-1

ImpurityCinacalcet Impurity 42Cat. No. P-C166-072

ImpurityCinacalcet Impurity 43Cat. No. P-C166-073CAS 312690-19-0

ImpurityCinacalcet Impurity 44Cat. No. P-C166-074CAS 308368-65-2

ImpurityCinacalcet Impurity 45Cat. No. P-C166-075CAS 10420-89-0

ImpurityCinacalcet Impurity 46Cat. No. P-C166-076CAS 927824-55-3

ImpurityCinacalcet Impurity 47 HydrochlorideCat. No. P-C166-077

ImpurityCinacalcet Impurity 48 HydrochlorideCat. No. P-C166-078

ImpurityCinacalcet Impurity 49 HydrochlorideCat. No. P-C166-079CAS 1093944-40-1

ImpurityCinacalcet Impurity 50Cat. No. P-C166-080

ImpurityDehydro Cinacalcet HydrochlorideCat. No. P-C166-082CAS 1207533-91-2

ImpurityCinacalcet 3-Methylphenyl Analog HydrochlorideCat. No. P-C166-084

ImpurityCinacalcet Cyclohexyl Analog Hydrochloride (Mixture of Diastereomers)Cat. No. P-C166-085

ImpurityCinacalcet N-Oxide Impurity HClCat. No. P-C166-086

ImpurityCinacalcet Naphthalen-2-yl Regioisomer HClCat. No. P-C166-087CAS 2200269-28-7

ImpurityEthyl[(1R)-1-(naphthalen-1-yl)ethyl]amineCat. No. P-C166-088CAS 133469-32-6

ImpurityCinacalcet Impurity 51Cat. No. P-C166-090CAS 104201-66-3

ImpurityCinacalcet Impurity 52Cat. No. P-C166-091CAS 1261456-46-5

ImpurityCinacalcet Impurity 53Cat. No. P-C166-092CAS 849442-21-3

ImpurityN-[1-(Naphthalen-1-yl)ethyl]formamideCat. No. P-C166-093CAS 49681-33-6

ImpurityCinacalcet AmideCat. No. P-C166-094CAS 1005450-55-4

Impurityrac-Cinacalcet HClCat. No. P-C166-095CAS 1025064-33-8

ImpurityTetrahydro Cinacalcet Impurity HClCat. No. P-C166-096CAS 1229225-43-7

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