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Family · Pharmaceutical analytical standards

Colchicine

An alkaloid of the autumn crocus (Colchicum autumnale), isolated in 1820 by the French pharmacists Pelletier and Caventou. The plant already appears in the Egyptian Ebers papyrus, around 1550 BC, and colchicine is still used against gout. This family brings together the active ingredient, pharmacopoeial impurities, metabolites, labelled standards, nitrosamines and other impurities.

Did you know?In 1937 Albert Blakeslee and Amos Avery discovered that it doubles the chromosomes of plant cells: since then it has been used to obtain polyploid plants in plant breeding.

ColchicineGo to the active ingredient →
ColchicineActive ingredientColchicineCat. No. P-C239-001CAS 64-86-8
Colchicine-d6Isotopically labelledColchicine-d6Cat. No. P-C239-017CAS 1217651-73-4
Demecolcine-d3Isotopically labelledDemecolcine-d3Cat. No. P-C239-018CAS 1217668-72-8
Demecolcine-d6Isotopically labelledDemecolcine-d6Cat. No. P-C239-019CAS 1217602-04-4

EDQM standards 1

The official European Pharmacopoeia standards for this family.

Reference substanceColchicine CRSEDQM code C2580000Family Colchicine

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