Family · Pharmaceutical analytical standards
Copper Tetramibi Tetrafluoroborate
A copper(I) complex carrying four MIBI (methoxyisobutylisonitrile) molecules: it is the freeze-dried precursor in kits for preparing technetium-99m sestamibi, a cardiac imaging tracer approved in the United States in 1990 and also used for parathyroid and breast imaging. This family brings together the active ingredient.
Did you know?In the kit the MIBI is held on copper: after 10 minutes in boiling water with pertechnetate it moves to technetium, which binds six of them, hence 'sesta' in the name. The tracer grew out of work by Alan Davison (MIT) and Alun Jones (Harvard).
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EDQM standards 1
The official European Pharmacopoeia standards for this family.
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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
