Family · Pharmaceutical analytical standards
Cycloguanil
An antimalarial that blocks dihydrofolate reductase, the enzyme the malaria parasite uses to make DNA building blocks: it is formed in the body from proguanil and was long considered mainly responsible for its action. This family brings together the active ingredient.
Did you know?Curiously, while proguanil boosts the effect of atovaquone, with which it is often combined, its metabolite cycloguanil counteracts it.
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