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Family · Pharmaceutical analytical standards

Deutetrabenazine

A vesicular monoamine transporter 2 (VMAT2) inhibitor, used for chorea in Huntington's disease and for tardive dyskinesia. It was approved in the US in 2017, the first deuterated drug to receive FDA approval. This family brings together metabolites.

Did you know?It is the 'heavy' version of tetrabenazine: six hydrogen atoms in its two methoxy groups are replaced by deuterium, an isotope of hydrogen that slows down the drug's metabolism.

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