Family · Pharmaceutical analytical standards

Erlotinib

An EGFR tyrosine kinase inhibitor, approved in 2004 for non-small cell lung cancer and later for pancreatic cancer. This family brings together the active ingredient, pharmacopoeial impurities, metabolites, labelled standards, nitrosamines and other impurities.

Did you know?Its effect also depends on the tumour's DNA: it works with or without mutations in the EGFR gene, but appears more effective when the gene is mutated.

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Active ingredientErlotinib HydrochlorideCat. No. P-E085-001CAS 183319-69-9

Active ingredientErlotinibCat. No. P-E085-002CAS 183321-74-6

Pharmacopoeial impurityErlotinib EP Impurity ACat. No. P-E085-003CAS 179688-29-0

Pharmacopoeial impurityErlotinib EP Impurity BCat. No. P-E085-004CAS 54060-30-9

Pharmacopoeial impurityErlotinib EP Impurity DCat. No. P-E085-005CAS 183322-18-1

Pharmacopoeial impurityErlotinib EP Impurity ECat. No. P-E085-006CAS 1058132-82-3

Pharmacopoeial impurityErlotinib EP Impurity FCat. No. P-E085-007CAS 1809951-10-7

Pharmacopoeial impurityErlotinib EP Impurity GCat. No. P-E085-008CAS 183322-19-2

Pharmacopoeial impurityErlotinib EP Impurity H HydrochlorideCat. No. P-E085-009CAS 183320-19-6

Pharmacopoeial impurityErlotinib EP Impurity ICat. No. P-E085-010CAS 183322-20-5

Pharmacopoeial impurityErlotinib EP Impurity JCat. No. P-E085-011CAS 183321-83-7

Pharmacopoeial impurityErlotinib EP Impurity KCat. No. P-E085-012CAS 2204518-92-1

Pharmacopoeial impurityErlotinib EP Impurity LCat. No. P-E085-013CAS 183321-82-6

Pharmacopoeial impurityErlotinib EP Impurity MCat. No. P-E085-014CAS 183322-21-6

MetaboliteErlotinib Hydroxy MetaboliteCat. No. P-E085-015CAS 882420-22-6

MetaboliteErlotinib Metabolite 2Cat. No. P-E085-017CAS 183320-29-8

MetaboliteErlotinib Metabolite 3Cat. No. P-E085-018CAS 183321-86-0

MetaboliteErlotinib Metabolite 3 HydrochlorideCat. No. P-E085-019CAS 183320-51-6

MetaboliteErlotinib Metabolite 2 HydrochlorideCat. No. P-E085-020CAS 183365-34-6

Isotopically labelledErlotinib EP Impurity B-d4Cat. No. P-E085-021CAS 1794883-73-0

Isotopically labelledErlotinib O-Desmethyl Metabolite Isomer (M-14)-d4 HClCat. No. P-E085-022

Isotopically labelledErlotinib-d6 HClCat. No. P-E085-024CAS 1189953-78-3

NitrosamineN-Nitroso ErlotinibCat. No. P-E085-025

Impurity2,4-DihydroxybenzaldehydeCat. No. P-E085-026CAS 95-01-2

ImpurityErlotinib Impurity 1Cat. No. P-E085-027CAS 1839513-98-2

ImpurityErlotinib Impurity 2Cat. No. P-E085-028CAS 1494468-76-6

ImpurityErlotinib Impurity 3Cat. No. P-E085-029CAS 236750-62-2

ImpurityErlotinib Impurity 4Cat. No. P-E085-030CAS 574738-66-2

ImpurityErlotinib Impurity 5 HydrochlorideCat. No. P-E085-031CAS 183322-17-0

ImpurityErlotinib Impurity 6Cat. No. P-E085-032CAS 950596-58-4

Impurity2-ethynylanilineCat. No. P-E085-033CAS 52670-38-9

Impurity3,4-Bis(2-methoxyethoxy)benzaldehydeCat. No. P-E085-034CAS 80407-64-3

ImpurityErlotinib Impurity 7Cat. No. P-E085-035CAS 183322-16-9

Impurity3,4-Bis(2-methoxyethoxy)benzonitrileCat. No. P-E085-036CAS 80407-68-7

Impurity3,4-DihydroxybenzaldehydeCat. No. P-E085-037CAS 139-85-5

Impurity3-(3-Nitrophenyl)-3-oxopropanalCat. No. P-E085-038CAS 154669-16-6

Impurity3-[2-(Trimethylsilyl)ethynyl]anilineCat. No. P-E085-039CAS 110598-30-6

Impurity3-AminobenzaldehydeCat. No. P-E085-040CAS 1709-44-0

Impurity3-AminostyreneCat. No. P-E085-041CAS 15411-43-5

Impurity3-BromoanilineCat. No. P-E085-042CAS 591-19-5

ImpurityErlotinib Impurity 8Cat. No. P-E085-043CAS 236750-65-5

ImpurityErlotinib Impurity 9Cat. No. P-E085-044CAS 938185-06-9

ImpurityErlotinib Impurity 10Cat. No. P-E085-045CAS 1683583-42-7

Impurity4-(3-Aminophenyl)-2-methylbut-3-yn-2-olCat. No. P-E085-046CAS 69088-96-6

ImpurityErlotinib Impurity 11Cat. No. P-E085-047CAS 175281-76-2

Impurity4-Methyl ErlotinibCat. No. P-E085-048CAS 1346601-52-2

ImpurityErlotinib Impurity 12Cat. No. P-E085-049CAS 1683583-39-2

ImpurityErlotinib Impurity 13Cat. No. P-E085-050CAS 1312937-41-9

ImpurityErlotinib Impurity 14Cat. No. P-E085-051CAS 1417161-98-8

ImpurityErlotinib Impurity 15Cat. No. P-E085-052CAS 299912-60-0

ImpurityErlotinib Impurity 16Cat. No. P-E085-053CAS 766497-25-0

Pharmacopoeial impurityErlotinib EP Impurity J HydrochlorideCat. No. P-E085-054CAS 183320-04-9

ImpurityErlotinib Impurity 17 (AMX3009)Cat. No. P-E085-055CAS 1879071-95-0

ImpurityDesethynyl ErlotinibCat. No. P-E085-056CAS 1145671-52-8

MetaboliteDesmethyl Erlotinib Carboxylate AcidCat. No. P-E085-057CAS 1170354-84-3

ImpurityDidesmethyl ErlotinibCat. No. P-E085-058CAS 183321-84-8

ImpurityErlotinib Carboxylic AcidCat. No. P-E085-059CAS 882420-21-5

ImpurityErlotinib DimerCat. No. P-E085-060

ImpurityErlotinib Impurity 19Cat. No. P-E085-062

ImpurityErlotinib Impurity 20Cat. No. P-E085-063

ImpurityErlotinib Impurity 21Cat. No. P-E085-065

ImpurityErlotinib Impurity 22Cat. No. P-E085-066

ImpurityErlotinib Impurity 23Cat. No. P-E085-067

ImpurityErlotinib Impurity 24Cat. No. P-E085-068

ImpurityErlotinib Impurity 25Cat. No. P-E085-069

ImpurityErlotinib Impurity 26Cat. No. P-E085-070

ImpurityErlotinib Impurity 27Cat. No. P-E085-071

ImpurityErlotinib Impurity 28Cat. No. P-E085-072

ImpurityErlotinib Impurity 29Cat. No. P-E085-073

ImpurityErlotinib Impurity 30 HydrochlorideCat. No. P-E085-074

ImpurityErlotinib Impurity 31Cat. No. P-E085-075

ImpurityErlotinib Impurity 32Cat. No. P-E085-076

ImpurityErlotinib Impurity 33Cat. No. P-E085-077

ImpurityErlotinib Impurity 34 HydrochlorideCat. No. P-E085-078

ImpurityErlotinib Impurity 35Cat. No. P-E085-079

ImpurityErlotinib Impurity 36Cat. No. P-E085-080

ImpurityErlotinib Impurity 37Cat. No. P-E085-081

ImpurityErlotinib Impurity 38Cat. No. P-E085-082

ImpurityErlotinib Impurity 39Cat. No. P-E085-083

ImpurityErlotinib Impurity 41Cat. No. P-E085-085

ImpurityErlotinib Impurity 42Cat. No. P-E085-086

ImpurityErlotinib Impurity 43Cat. No. P-E085-087

ImpurityErlotinib Impurity 44Cat. No. P-E085-088

ImpurityErlotinib Impurity 45Cat. No. P-E085-089

ImpurityErlotinib Impurity 46Cat. No. P-E085-090

ImpurityErlotinib Impurity 47Cat. No. P-E085-091

ImpurityErlotinib Impurity 49Cat. No. P-E085-093

ImpurityErlotinib Impurity 50Cat. No. P-E085-094CAS 1384975-87-4

ImpurityErlotinib Impurity 51Cat. No. P-E085-095

ImpurityErlotinib Impurity 52Cat. No. P-E085-096

ImpurityErlotinib Impurity 53Cat. No. P-E085-097

ImpurityErlotinib Impurity 54Cat. No. P-E085-098

ImpurityErlotinib Impurity 55Cat. No. P-E085-099

ImpurityErlotinib Impurity 56Cat. No. P-E085-100

ImpurityErlotinib Impurity 57Cat. No. P-E085-102CAS 1058651-74-3

ImpurityErlotinib Impurity 58Cat. No. P-E085-103CAS 2218487-28-4

ImpurityErlotinib Impurity 59Cat. No. P-E085-104CAS 1318599-96-0

ImpurityErlotinib Impurity 60Cat. No. P-E085-105CAS 1318600-03-1

ImpurityErlotinib Impurity 61Cat. No. P-E085-106

ImpurityErlotinib Impurity 62Cat. No. P-E085-107CAS 2221937-43-3

ImpurityErlotinib Impurity 63Cat. No. P-E085-108

ImpurityErlotinib Impurity 64Cat. No. P-E085-109CAS 2055840-54-3

ImpurityErlotinib Impurity 65Cat. No. P-E085-110

ImpurityErlotinib Impurity 66Cat. No. P-E085-111

ImpurityErlotinib Impurity 67Cat. No. P-E085-112CAS 1620397-61-6

ImpurityEthyl 3,4-dihydroxybenzoateCat. No. P-E085-117CAS 3943-89-3

ImpurityErlotinib Impurity 70Cat. No. P-E085-118CAS 1012057-39-4

ImpurityErlotinib Impurity 71Cat. No. P-E085-119CAS 179688-26-7

Impuritym-ToluidineCat. No. P-E085-120CAS 108-44-1

ImpurityErlotinib Impurity 72Cat. No. P-E085-121CAS 950596-59-5

ImpurityErlotinib Impurity 73Cat. No. P-E085-122CAS 328528-74-1

ImpurityN-(3-Desethynylphenyl)-N-(3-bromophenyl) Erlotinib HydrochlorideCat. No. P-E085-124CAS 2055840-41-8

ImpurityErlotinib Impurity 74Cat. No. P-E085-125CAS 1029721-32-1

ImpurityN-Methoxyethyl Erlotinib HClCat. No. P-E085-126

EDQM standards 1

The official European Pharmacopoeia standards for this family.

Reference substanceErlotinib hydrochloride CRSEDQM code Y0002444Family Erlotinib

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