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Family · Pharmaceutical analytical standards

Etravirine

A second-generation HIV non-nucleoside reverse transcriptase inhibitor, approved in the United States in January 2008 for previously treated patients whose virus has become resistant to other drugs. This family brings together the active ingredient, pharmacopoeial impurities, labelled standards, nitrosamines and other impurities.

Did you know?It is a highly flexible diarylpyrimidine: it can adopt several conformations in the enzyme's pocket, which helps it keep binding even when the virus mutates.

EtravirineGo to the active ingredient →
EtravirineActive ingredientEtravirineCat. No. P-E142-001CAS 269055-15-4
Etravirine-d4Isotopically labelledEtravirine-d4Cat. No. P-E142-006CAS 1142095-93-9
Etravirine-d6Isotopically labelledEtravirine-d6Cat. No. P-E142-007CAS 1142096-06-7

EDQM standards 1

The official European Pharmacopoeia standards for this family.

Reference substanceEtravirine CRSEDQM code Y0002455Family Etravirine

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