Family · Pharmaceutical analytical standards
Etravirine
A second-generation HIV non-nucleoside reverse transcriptase inhibitor, approved in the United States in January 2008 for previously treated patients whose virus has become resistant to other drugs. This family brings together the active ingredient, pharmacopoeial impurities, labelled standards, nitrosamines and other impurities.
Did you know?It is a highly flexible diarylpyrimidine: it can adopt several conformations in the enzyme's pocket, which helps it keep binding even when the virus mutates.
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EDQM standards 1
The official European Pharmacopoeia standards for this family.
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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
