Family · Pharmaceutical analytical standards
Exatecan
A hexacyclic, water-soluble derivative of camptothecin that blocks topoisomerase I, studied as an anticancer drug in the 1990s; today a derivative of it, deruxtecan, is the payload of several antibody-drug conjugates. This family brings together the active ingredient and metabolites.
Did you know?It descends from camptothecin, discovered in 1966 in the bark of Camptotheca acuminata, a Chinese tree whose local name means "happy tree".
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