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Family · Pharmaceutical analytical standards

Exemestane

An irreversible steroidal inactivator of aromatase, the enzyme that makes oestrogens; approved in the United States in 1999, it is used in hormone-dependent breast cancer in postmenopausal women. This family brings together the active ingredient, pharmacopoeial impurities, metabolites, labelled standards and other impurities.

Did you know?Developed in Italy in the 1980s, it mimics androstenedione, the enzyme's natural substrate, and binds to it permanently: this is why it is called a suicide inhibitor.

ExemestaneGo to the active ingredient →
ExemestaneActive ingredientExemestaneCat. No. P-E147-001CAS 107868-30-4

EDQM standards 2

The official European Pharmacopoeia standards for this family.

Reference substanceExemestane CRSEDQM code Y0001747Family Exemestane

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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.