Family · Pharmaceutical analytical standards
Fexofenadine
A second-generation antihistamine in use since 1996 for allergic rhinitis and hives: it is the active metabolite of terfenadine and barely crosses the blood-brain barrier, which is why it rarely causes drowsiness. This family brings together the active ingredient, pharmacopoeial impurities, labelled standards, nitrosamines and other impurities.
Did you know?Grapefruit juice, and orange and apple juice too, reduces its absorption: it probably blocks OATP1A2, a gut transporter that helps the medicine enter the body.
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EDQM standards 4
The official European Pharmacopoeia standards for this family.
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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
