Family · Pharmaceutical analytical standards
Griselimycin
A natural antibiotic discovered in the 1960s and then shelved: it blocks the bacterial DNA 'clamp' (the DnaN protein), essential for copying DNA, and has returned to the spotlight as a candidate against tuberculosis. This family brings together the active ingredient.
Did you know?It lay forgotten for about half a century: in 2015 an international team optimised a variant, cyclohexylgriselimycin, which works even when taken by mouth against the tuberculosis bacillus.
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