Family · Pharmaceutical analytical standards

Hydrochlorothiazide

A thiazide diuretic that helps the kidneys eliminate sodium and water: introduced in 1959, it is used for hypertension, often combined with other antihypertensives. This family brings together the active ingredient, pharmacopoeial impurities, labelled standards, nitrosamines and other impurities.

Did you know?It descends from chlorothiazide, the first thiazide diuretic, introduced in 1958: its discoverers Karl Beyer, James Sprague, John Baer and Frederick Novello received a special Lasker Award in 1975.

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Active ingredientHydrochlorothiazideCat. No. P-H038-001CAS 58-93-5

Pharmacopoeial impurityHydrochlorothiazide EP Impurity BCat. No. P-H038-002CAS 121-30-2

Pharmacopoeial impurityHydrochlorothiazide EP Impurity CCat. No. P-H038-003CAS 402824-96-8

Isotopically labelled4-Nitroso Hydrochlorothiazide-13C-d2Cat. No. P-H038-004

Isotopically labelledHydrochlorothiazide EP Impurity B-15N2Cat. No. P-H038-005CAS 446877-58-3

Isotopically labelledHydrochlorothiazide-13C-d2Cat. No. P-H038-006CAS 1190006-03-1

Isotopically labelledHydrochlorothiazide-15N2-13C-d2Cat. No. P-H038-007CAS 2140316-81-8

Isotopically labelledHydrochlorothiazide-d2Cat. No. P-H038-008CAS 1219798-89-6

Isotopically labelledN4-Nitroso Hydrochlorothiazide-13C-15N2-d2Cat. No. P-H038-009

NitrosamineN-Nitroso 5-Chloro Hydrochlorothiazide-1Cat. No. P-H038-010

NitrosamineN-Nitroso 5-Chloro Hydrochlorothiazide-2Cat. No. P-H038-011

NitrosamineN-Nitroso HydrochlorothiazideCat. No. P-H038-012CAS 63779-86-2

NitrosamineN-Nitroso Hydrochlorothiazide EP Impurity C-1Cat. No. P-H038-013

NitrosamineN-Nitroso Hydrochlorothiazide EP Impurity C-2Cat. No. P-H038-014

NitrosamineN-Nitroso Hydrochlorothiazide EP Impurity C-3Cat. No. P-H038-015

NitrosamineN-Nitroso Hydrochlorothiazide EP Impurity C-4Cat. No. P-H038-016

ImpurityHydrochlorothiazide Impurity 1Cat. No. P-H038-017CAS 90794-87-9

Impurity(N-[(2-Aminophenyl)sulfonyl] Acetamide)Cat. No. P-H038-018CAS 75304-18-6

Impurity4H-1,2,4-Benzothiadiazine-7-sulfonamide 1,1-DioxideCat. No. P-H038-019CAS 23141-75-5

ImpurityHydrochlorothiazide Impurity 2Cat. No. P-H038-020CAS 133121-37-6

Impurity2-Amino-4-chlorobenzenesulphonamideCat. No. P-H038-021CAS 4140-83-4

Impurity2-Amino-5-chlorobenzenesulphonamideCat. No. P-H038-022CAS 5790-69-2

ImpurityMebetideCat. No. P-H038-023CAS 360-81-6

ImpurityHydrochlorothiazide Impurity 3Cat. No. P-H038-024CAS 364-96-5

Impurity3-Chloro-5-nitrobenzenesulfonamideCat. No. P-H038-025CAS 957785-35-2

Impurity4-Amino-2-chlorobenzene-1-sulfonamideCat. No. P-H038-026CAS 1954-94-5

Impurity4-Amino-5,6-dichlorobenzene-1,3-disulfonamideCat. No. P-H038-027CAS 5250-72-6

ImpurityHydrochlorothiazide Impurity 4Cat. No. P-H038-028CAS 1083-36-9

ImpurityHydrochlorothiazide Impurity 5Cat. No. P-H038-029CAS 671-89-6

ImpurityHydrochlorothiazide Impurity 6Cat. No. P-H038-030CAS 99418-26-5

ImpurityHydrochlorothiazide Impurity 7Cat. No. P-H038-031CAS 85119-88-6

Impurity4-Aminobenzene-1,3-disulfonamideCat. No. P-H038-032CAS 40642-90-8

Impurity5-ChlorohydrochlorothiazideCat. No. P-H038-033CAS 5233-42-1

Impurity5-Nitro-1,3-benzenedisulfonamideCat. No. P-H038-034CAS 69031-67-0

ImpurityHydrochlorothiazide Impurity 8Cat. No. P-H038-035CAS 1668-63-9

ImpurityHydrochlorothiazide Impurity 9Cat. No. P-H038-036CAS 89813-56-9

ImpurityHydrochlorothiazide Impurity 10Cat. No. P-H038-037CAS 22503-74-8

ImpurityHydrochlorothiazide Impurity 11Cat. No. P-H038-038CAS 2089381-36-0

ImpurityHydrochlorothiazide Impurity 13Cat. No. P-H038-040

ImpurityHydrochlorothiazide Impurity 14Cat. No. P-H038-041

ImpurityHydrochlorothiazide Impurity 15Cat. No. P-H038-042

ImpurityHydrochlorothiazide Impurity 16Cat. No. P-H038-043CAS 82205-98-9

ImpurityHydrochlorothiazide Impurity 17Cat. No. P-H038-044CAS 856302-12-0

ImpurityHydrochlorothiazide Impurity 18Cat. No. P-H038-045CAS 24611-78-7

ImpurityHydrochlorothiazide Impurity 19Cat. No. P-H038-046

ImpurityHydrochlorothiazide Impurity 20Cat. No. P-H038-047

ImpurityHydrochlorothiazide Impurity 21Cat. No. P-H038-048

ImpurityHydrochlorothiazide Impurity 22Cat. No. P-H038-051

ImpurityHydrochlorothiazide Impurity 23Cat. No. P-H038-052

ImpurityHydrochlorothiazide Impurity 24Cat. No. P-H038-053

ImpurityHydrochlorothiazide Impurity 25Cat. No. P-H038-054

ImpurityHydrochlorothiazide Impurity 26Cat. No. P-H038-055CAS 289907-38-6

ImpurityHydrochlorothiazide Impurity 27Cat. No. P-H038-057

ImpurityHydrochlorothiazide Impurity 28Cat. No. P-H038-058

ImpurityHydrochlorothiazide Impurity 29Cat. No. P-H038-059

ImpurityHydrothiazideCat. No. P-H038-060CAS 23141-82-4

ImpurityHydrochlorothiazide Impurity 30Cat. No. P-H038-061CAS 1753-71-5

EDQM standards 2

The official European Pharmacopoeia standards for this family.

Reference substanceHydrochlorothiazide CRSEDQM code H1200000Family Hydrochlorothiazide

Structure not applicable: mixtureFor peak identificationHydrochlorothiazide for peak identification CRSEDQM code Y0001494Family Hydrochlorothiazide

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