Family · Pharmaceutical analytical standards
Lobucavir
A guanine nucleoside analogue in which the sugar is replaced by a cyclobutane ring, active against herpesviruses, cytomegalovirus, hepatitis B virus and HIV: studied in the 1990s up to phase III, its clinical development was stopped in 1999. This family brings together the active ingredient and labelled standards.
Did you know?Unlike classic chain terminators, which stop the copying of viral DNA at the point where they are inserted, it appears to block the polymerase two or three nucleotides further along.
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