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Family · Pharmaceutical analytical standards

Lonafarnib

A farnesyltransferase inhibitor first developed as a potential cancer drug and approved in the United States in November 2020 as the first treatment for Hutchinson-Gilford progeria and some progeroid laminopathies. This family brings together the active ingredient, labelled standards and other impurities.

Did you know?It blocks the attachment of a farnesyl group to progerin, the faulty protein thought to cause progeria. The first-ever clinical trial in this rare disease began in 2007.

LonafarnibGo to the active ingredient →
LonafarnibActive ingredientLonafarnibCat. No. P-L088-001CAS 193275-84-2

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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.