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Family · Pharmaceutical analytical standards

Loratadine

A second-generation antihistamine that blocks histamine H1 receptors, patented in 1980 and marketed since 1988: it is used for allergic rhinitis and hives, with little drowsiness because it barely crosses the blood-brain barrier. This family brings together the active ingredient, pharmacopoeial impurities, labelled standards and other impurities.

Did you know?Its three-ring structure closely resembles that of tricyclic antidepressants such as imipramine, yet its effect is quite different: it blocks histamine receptors.

LoratadineGo to the active ingredient →
LoratadineActive ingredientLoratadineCat. No. P-L092-001CAS 79794-75-5
Loratadine-d5Isotopically labelledLoratadine-d5Cat. No. P-L092-011CAS 1020719-57-6

EDQM standards 6

The official European Pharmacopoeia standards for this family.

Reference substanceLoratadine CRSEDQM code Y0000688Family Loratadine

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