Family · Pharmaceutical analytical standards
Maytansine
An antitumour macrolide isolated in 1972 from the Ethiopian shrub Maytenus serrata: it binds tubulin and blocks microtubules, halting cell division. This family brings together the active ingredient and other impurities.
Did you know?Too toxic to be used on its own, it now travels aboard antibodies: its derivatives, the maytansinoids, are the payload of antibody-drug conjugates such as trastuzumab emtansine.
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