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Family · Pharmaceutical analytical standards

Maytansinol

The alcohol core of the maytansinoids, ansamycin-type anticancer agents that block tubulin: it is obtained by removing the ester side chain of ansamitocin P-3, made by fermentation of the bacterium Actinosynnema pretiosum, and is the key intermediate for making DM1 for antibody-drug conjugates. This family brings together the active ingredient and labelled standards.

Did you know?The parent of the family, maytansine, was first reported in 1972 by Kupchan and colleagues: it comes from shrubs of the genus Maytenus, which gave it its name.

MaytansinolGo to the active ingredient →
MaytansinolActive ingredientMaytansinolCat. No. P-M016-001CAS 57103-68-1

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