Active ingredientMefatinib (Mixture of Z and E Isomers)Cat. No. P-M031-001CAS 1417695-74-9Family · Pharmaceutical analytical standards
Mefatinib
An experimental irreversible second-generation inhibitor of the EGFR and HER2 tyrosine kinases, studied in China as a first-line treatment for non-small cell lung cancer with EGFR mutations. This family brings together the active ingredient, labelled standards, nitrosamines and other impurities.
Did you know?In the phase Ib/II study published in 2021 in 106 patients, the most common resistance mechanism was the EGFR T790M mutation, found in 42% of the tumours that had stopped responding.
Go to the active ingredient →Active ingredientMefatinib (Mixture of Z and E Isomers)Cat. No. P-M031-001CAS 1417695-74-9
Active ingredientMefatinib MalateCat. No. P-M031-002CAS 1989592-50-8
Isotopically labelledMefatinib-d6 MalateCat. No. P-M031-003
NitrosamineN-Nitroso N-Desmethyl MefatinibCat. No. P-M031-004
Impurity(E)-MefatinibCat. No. P-M031-008CAS 1639014-72-4
ImpurityMefatinib Impurity 1Cat. No. P-M031-009CAS 1417695-75-0
Impurity6-Nitroquinazoline-4,7-diolCat. No. P-M031-010CAS 574738-64-0
ImpurityMefatinib Impurity 2Cat. No. P-M031-011CAS 2225147-32-8
ImpurityMefatinib Impurity 3Cat. No. P-M031-012CAS 1417695-76-1
Impurity7-Chloro-6-nitro-4-quinazolinolCat. No. P-M031-013CAS 53449-14-2
Impurity7-Methoxy-6-nitroquinazolin-4(3H)-oneCat. No. P-M031-014CAS 1012057-47-4
ImpurityMefatinib Impurity 4Cat. No. P-M031-015
ImpurityMefatinib Impurity 5Cat. No. P-M031-017
ImpurityMefatinib Impurity 6Cat. No. P-M031-018
ImpurityMefatinib Impurity 7Cat. No. P-M031-019
ImpurityMefatinib Impurity 8Cat. No. P-M031-021CAS 1417695-77-2
ImpurityMefatinib Impurity 9Cat. No. P-M031-022CAS 1417695-78-3
ImpurityMefatinib Impurity 10Cat. No. P-M031-023
ImpurityMefatinib Impurity 11Cat. No. P-M031-024No product matches your search.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.