Active ingredientMelagatranCat. No. P-M036-001CAS 159776-70-2Family · Pharmaceutical analytical standards
Melagatran
A direct thrombin inhibitor, blocking the key enzyme of blood clotting: it is the active form of ximelagatran, an oral anticoagulant marketed in some European countries in the mid-2000s and withdrawn in 2006. This family brings together the active ingredient.
Did you know?It was designed starting from the crystal structure of thrombin bound to an inhibitor; since it was poorly absorbed by mouth, it was turned into a 'double prodrug', ximelagatran, the first oral direct thrombin inhibitor to enter clinical trials.
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