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Family · Pharmaceutical analytical standards

Melatonin

A hormone produced by the pineal gland mainly at night: it signals darkness to the body and regulates the sleep-wake rhythm. It was isolated in 1958 by dermatologist Aaron B. Lerner and his team at Yale University, from bovine pineal gland extracts. This family brings together the active ingredient, pharmacopoeial impurities, metabolites, labelled standards, nitrosamines and other impurities.

Did you know?As early as 1917 it was seen that extracts of cow pineal glands lightened the skin of tadpoles; the name comes from the Greek melas (black) and tonos, on the model of serotonin.

MelatoninGo to the active ingredient →
MelatoninActive ingredientMelatoninCat. No. P-M037-001CAS 73-31-4
Melatonin-d4Isotopically labelledMelatonin-d4Cat. No. P-M037-008CAS 66521-38-8
Melatonin-d7Isotopically labelledMelatonin-d7Cat. No. P-M037-009CAS 615251-68-8

EDQM standards 2

The official European Pharmacopoeia standards for this family.

Reference substanceMelatonin CRSEDQM code Y0002329Family Melatonin

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