Family · Pharmaceutical analytical standards
Methylnaltrexone
A peripherally acting mu-opioid receptor antagonist: as a quaternary ammonium cation it cannot cross the blood-brain barrier, so it counters opioid-induced constipation without removing pain relief in the brain. It was approved in the US in 2008. This family brings together the active ingredient, labelled standards and other impurities.
Did you know?The idea was born in 1978, when pharmacologist Leon Goldberg of the University of Chicago looked for a way to free a sick friend from morphine-induced constipation without taking away his pain relief.
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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
