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Monic Acid A

A 17-carbon polyketide that forms the core of mupirocin (pseudomonic acid A), an antibiotic isolated in 1971 from the bacterium Pseudomonas fluorescens: in mupirocin it is joined as an ester to 9-hydroxynonanoic acid. This family brings together the active ingredient and labelled standards.

Did you know?In mupirocin it is monic acid itself, the molecule's 'head', that resembles isoleucyl-adenylate: this way the antibiotic fools the bacterial enzyme that loads isoleucine onto tRNA and halts the bacteria's protein production.

Monic Acid AGo to the active ingredient →
Monic Acid AActive ingredientMonic Acid ACat. No. P-M164-001CAS 66262-68-8

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