Active ingredientNeratinibCat. No. P-N038-001CAS 698387-09-6Family · Pharmaceutical analytical standards
Neratinib
A tyrosine kinase inhibitor of HER2, EGFR and HER4, approved in the United States in 2017 and in Europe in 2018 for early-stage HER2-positive breast cancer, as extended adjuvant therapy after trastuzumab. This family brings together the active ingredient, labelled standards, nitrosamines and other impurities.
Did you know?It forms a covalent, in other words permanent, bond with a cysteine in the HER2 and EGFR receptors: this is why it stays active even against the EGFR T790M variant, which escapes non-covalent inhibitors.
Go to the active ingredient →Active ingredientNeratinibCat. No. P-N038-001CAS 698387-09-6
Isotopically labelledNeratinib-d6Cat. No. P-N038-002CAS 1259519-18-0
NitrosamineN2-Nitroso NeratinibCat. No. P-N038-005
ImpurityNeratinib bis-N-OxideCat. No. P-N038-006
ImpurityNeratinib Impurity 1Cat. No. P-N038-007CAS 342910-13-8
ImpurityMethyl 3-acetamido-4-ethoxybenzoateCat. No. P-N038-008CAS 1201080-20-7
ImpurityNeratinib Impurity 2Cat. No. P-N038-009CAS 1801882-06-3
ImpurityNeratinib Impurity 3Cat. No. P-N038-010CAS 1222172-49-7
ImpurityNeratinib Impurity 4Cat. No. P-N038-011CAS 1201080-23-0
ImpurityN-Desmethyl NeratinibCat. No. P-N038-012CAS 915788-27-1
ImpurityNeratinib dimethylamine N-oxideCat. No. P-N038-013CAS 1376615-55-2
ImpurityNeratinib Impurity 5Cat. No. P-N038-014
ImpurityNeratinib Impurity 6Cat. No. P-N038-015
ImpurityNeratinib Impurity 7Cat. No. P-N038-016
ImpurityNeratinib Impurity 8Cat. No. P-N038-017
ImpurityNeratinib Impurity 9Cat. No. P-N038-019CAS 136571-66-9
ImpurityNeratinib Impurity 10Cat. No. P-N038-020CAS 848139-78-6
ImpurityNeratinib Impurity 11Cat. No. P-N038-024
ImpurityNeratinib Impurity 12Cat. No. P-N038-030
ImpurityNeratinib Impurity 13Cat. No. P-N038-031CAS 1348481-03-7
ImpurityNeratinib Impurity 14Cat. No. P-N038-032
ImpurityNeratinib Impurity 15Cat. No. P-N038-033
ImpurityNeratinib Impurity 16Cat. No. P-N038-034
ImpurityNeratinib Impurity 17Cat. No. P-N038-035
ImpurityNeratinib Impurity 18Cat. No. P-N038-036
ImpurityNeratinib pyridine N-oxideCat. No. P-N038-037CAS 1376619-94-1No product matches your search.
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