Family · Pharmaceutical analytical standards
Nicotinaldehyde Thiosemicarbazone
The thiosemicarbazone of nicotinaldehyde (pyridine-3-carbaldehyde), developed in 1950 by the chemist A. Girard as a less toxic variant of thioacetazone: that same year it showed a marked effect on experimental tuberculosis in mice, confirmed in 1951. This family brings together the active ingredient.
Did you know?It belongs to the same line of research on pyridine thiosemicarbazones that, in the early 1950s, preceded the discovery of isoniazid's antituberculosis activity.
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