Family · Pharmaceutical analytical standards
Nosiheptide
A thiopeptide antibiotic produced by the bacterium Streptomyces actuosus, active mainly against Gram-positive bacteria: it blocks protein synthesis by binding to the ribosome and is used as a feed additive for poultry and pigs. This family brings together the active ingredient.
Did you know?It is a peptide built by the ribosome and then heavily remodelled: it contains five thiazole rings and six sulfur atoms, and its first macrocycle closes through a Diels-Alder-type reaction.
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