Family · Pharmaceutical analytical standards
Novobiocin
An aminocoumarin antibiotic produced by Streptomyces niveus, described in the mid-1950s under the name streptonivicin: it blocks bacterial DNA gyrase by binding to its GyrB subunit. This family brings together the active ingredient.
Did you know?In microbiology it is still used to tell apart two similar staphylococci: Staphylococcus epidermidis is susceptible, Staphylococcus saprophyticus is not. Researchers also study it against polymerase theta.
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