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Family · Pharmaceutical analytical standards

Obeticholic Acid

A semi-synthetic derivative of chenodeoxycholic acid, a natural bile acid, that activates the nuclear receptor FXR, involved in regulating bile acids. Approved in the United States in 2016 for primary biliary cholangitis, together with ursodeoxycholic acid or alone when that is not tolerated. This family brings together the active ingredient, metabolites, labelled standards and other impurities.

Did you know?It was designed at the University of Perugia by the group of chemist Roberto Pellicciari by adding an ethyl group to the natural bile acid: it was the first FXR agonist to be studied in humans.

Obeticholic AcidGo to the active ingredient →

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