Family · Pharmaceutical analytical standards
Patupilone
The name of epothilone B, a natural macrolide isolated between the late 1980s and the early 1990s from the soil myxobacterium Sorangium cellulosum: it blocks cell division by stabilising microtubules, like paclitaxel, and was studied as an anticancer drug up to phase III, without reaching approval. This family brings together the active ingredient.
Did you know?Epothilones were first explored as antifungal agents for agriculture, before their powerful anticancer activity was discovered.
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