Family · Pharmaceutical analytical standards
Pitavastatin
A statin discovered in Japan, patented in 1987 and approved in 2003: it inhibits HMG-CoA reductase, the key enzyme in cholesterol synthesis, and is used to lower LDL cholesterol. It reached the United States in 2009. This family brings together the active ingredient, metabolites, labelled standards and other impurities.
Did you know?Unlike many other statins it barely uses the cytochrome P450 system, and CYP3A4 not at all: it is cleared mainly by glucuronidation.
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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
