Family · Pharmaceutical analytical standards
Polymyxin B
A polypeptide antibiotic made by the bacterium Paenibacillus polymyxa, discovered in 1947 and approved in the United States in 1964: it disrupts the membranes of Gram-negative bacteria and is now a reserve antibiotic, also used on the skin. This family brings together the active ingredient and other impurities.
Did you know?Fixed onto fibres inside a cartridge, it is used to cleanse the blood in septic shock: the drug stays bound to the fibres and captures the bacterial endotoxin that triggers the shock.
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EDQM standards 2
The official European Pharmacopoeia standards for this family.
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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
