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Family · Pharmaceutical analytical standards

Polymyxin B

A polypeptide antibiotic made by the bacterium Paenibacillus polymyxa, discovered in 1947 and approved in the United States in 1964: it disrupts the membranes of Gram-negative bacteria and is now a reserve antibiotic, also used on the skin. This family brings together the active ingredient and other impurities.

Did you know?Fixed onto fibres inside a cartridge, it is used to cleanse the blood in septic shock: the drug stays bound to the fibres and captures the bacterial endotoxin that triggers the shock.

Polymyxin B SulfateGo to the active ingredient →
Polymyxin B1Active ingredientPolymyxin B1Cat. No. P-P153-002CAS 4135-11-9
Polymyxin B2Active ingredientPolymyxin B2Cat. No. P-P153-003CAS 34503-87-2
Polymyxin B3Active ingredientPolymyxin B3Cat. No. P-P153-004CAS 71140-58-4

EDQM standards 2

The official European Pharmacopoeia standards for this family.

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