Family · Pharmaceutical analytical standards
Raltitrexed
An antimetabolite similar to folic acid that blocks thymidylate synthase, an enzyme needed to build DNA: since the late 1990s it has been used against colorectal cancer, and it has also been proposed for malignant mesothelioma. This family brings together the active ingredient, labelled standards and other impurities.
Did you know?Inside the cell it is linked to several glutamate molecules: in this 'polyglutamated' form it reaches full activity and can no longer get out, staying in the tissue for a long time.
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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
