Family · Pharmaceutical analytical standards
Resatorvid
A small molecule that blocks the TLR4 receptor, one of the sentinels of innate immunity, from inside the cell: it was studied against sepsis up to phase III, but the trial was stopped for lack of efficacy. This family brings together the active ingredient.
Did you know?It binds directly to a single amino acid of the receptor, cysteine 747, preventing it from talking to the proteins that pass on the inflammatory signal: today it is a widely used tool in biological research.
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